DGKQ antibody (C-Term)

Catalog No. ABIN6258763

Product Details anti-DGKQ Antibody

Target: DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKQ antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: DAGK Antibody detects endogenous levels of total DAGK.

Predicted Reactivity: Pig,Bovine,Horse,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DAGK, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DGKQ

Target: DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

Alternative Name: DGKQ (DGKQ Products)

Synonyms: DAGK antibody, DAGK4 antibody, DAGK7 antibody, 110kDa antibody, Dagk4 antibody, Dgkd antibody, diacylglycerol kinase theta antibody, diacylglycerol kinase, theta antibody, diacylglycerol kinase, theta, putative antibody, DGKQ antibody, Dgkq antibody, Smp_163080 antibody, Tsp_13406 antibody

Background:

Description: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.

Gene: DGKQ

Molecular Weight: 101 kDa

Gene ID: 1609

UniProt: P52824