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SETDB2 antibody (N-Term)

SETDB2 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258755
  • Target See all SETDB2 Antibodies
    SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
    Binding Specificity
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 18
    • 16
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 4
    • 1
    Rabbit
    Clonality
    • 29
    • 4
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETDB2 antibody is un-conjugated
    Application
    • 25
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    SETDB2 Antibody detects endogenous levels of total SETDB2.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SETDB2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SETDB2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
    Alternative Name
    SETDB2 (SETDB2 Products)
    Synonyms
    C13orf4 antibody, CLLD8 antibody, CLLL8 antibody, KMT1F antibody, Clld8 antibody, Gm293 antibody, SET domain bifurcated 2 antibody, SET domain, bifurcated 2 antibody, SETDB2 antibody, Setdb2 antibody
    Background

    Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

    Gene: SETDB2

    Molecular Weight
    120 kDa
    Gene ID
    83852
    UniProt
    Q96T68
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