BIN2 antibody (Internal Region)

Catalog No. ABIN6258711

Product Details anti-BIN2 Antibody

Target: BIN2 (Bridging Integrator 2 (BIN2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: BIN2 Antibody detects endogenous levels of total BIN2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BIN2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for BIN2

Target: BIN2 (Bridging Integrator 2 (BIN2))

Alternative Name: BIN2 (BIN2 Products)

Synonyms: BRAP-1 antibody, BIN2 antibody, bin2l antibody, wu:fi05e01 antibody, zgc:55758 antibody, bridging integrator 2 antibody, bridging integrator 2b antibody, BIN2 antibody, Bin2 antibody, bin2b antibody

Background:

Description: Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.

Gene: BIN2

Molecular Weight: 62 kDa

Gene ID: 51411

UniProt: Q9UBW5