TAB2 antibody (Internal Region)
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- Target See all TAB2 Antibodies
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAB2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- TAB2 Antibody detects endogenous levels of total TAB2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TAB2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TAB2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
- Alternative Name
- TAB2 (TAB2 Products)
- Synonyms
- CHTD2 antibody, MAP3K7IP2 antibody, 1110030N06Rik antibody, A530078N03Rik antibody, Map3k7ip2 antibody, mKIAA0733 antibody, map3k7ip2 antibody, zgc:77446 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 2 antibody, TAB2 antibody, Tab2 antibody, tab2 antibody
- Background
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Description: Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Gene: TAB2
- Molecular Weight
- 76 kDa
- Gene ID
- 23118
- UniProt
- Q9NYJ8
- Pathways
- TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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