ACSS1 antibody (C-Term)

Catalog No. ABIN6258660

Product Details anti-ACSS1 Antibody

Target: ACSS1 (Acyl-CoA Synthetase Short-Chain Family Member 1 (ACSS1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ACSS1 Antibody detects endogenous levels of total ACSS1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ACSS1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-ACSS1 antibody (ABIN6258660)

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Target Details for ACSS1

Target: ACSS1 (Acyl-CoA Synthetase Short-Chain Family Member 1 (ACSS1))

Alternative Name: ACSS1 (ACSS1 Products)

Synonyms: ACAS2L antibody, cb395 antibody, sb:cb395 antibody, wu:fa05a10 antibody, wu:fc49f03 antibody, wu:fi28d10 antibody, zgc:113194 antibody, zgc:158738 antibody, ACECS1 antibody, AceCS2L antibody, 1110032O15Rik antibody, AI788978 antibody, Acas2 antibody, Acas2l antibody, AceCS2 antibody, acyl-CoA synthetase short chain family member 1 antibody, acyl-CoA synthetase short-chain family member 1 antibody, acetyl-coenzyme A synthetase 2-like, mitochondrial antibody, ACSS1 antibody, acss1 antibody, LOC100541607 antibody, Acss1 antibody

Background:

Description: Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO2.

Gene: ACSS1

Molecular Weight: 75 kDa

Gene ID: 84532

UniProt: Q9NUB1