CCRK antibody (C-Term)

Catalog No. ABIN6258618

Product Details anti-CCRK Antibody

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCRK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CDK20 Antibody detects endogenous levels of total CDK20.

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDK20, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CCRK

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Alternative Name: CDK20 (CDK20 Products)

Background:

Description: Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

Gene: CDK20

Molecular Weight: 39 kDa

Gene ID: 23552

UniProt: Q8IZL9