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SLC4A8/10 antibody

SLC4A8/10 Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258561
  • Target See all SLC4A8/10 products
    SLC4A8/10 (Solute Carrier Family 4, Member 8/10 (SLC4A8/10))
    Reactivity
    Human, Mouse, Rat
    Host
    • 11
    Rabbit
    Clonality
    • 11
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC4A8/10 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    SLC4A8/10 Antibody detects endogenous levels of total SLC4A8/10
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotype
    IgG
  • Application Notes
    WB 1:500~1:1000, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    SLC4A8/10 (Solute Carrier Family 4, Member 8/10 (SLC4A8/10))
    Alternative Name
    SLC4A8/10 (SLC4A8/10 Products)
    Background

    Description: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3- exchange with a Na+:HCO3- stoichiometry of 2:1. Plays a major role in  pH regulation in neurons. May be involved in cell  pH regulation by transporting HCO3- from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3- into the cells. Also mediates lithium-dependent HCO3- cotransport. May be regulated by osmolarity.

    Gene: SLC4A8

    Molecular Weight
    140 kDa
    Gene ID
    9498
    UniProt
    Q2Y0W8, Q6U841
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