SLC4A8/10 antibody
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- Target See all SLC4A8/10 products
- SLC4A8/10 (Solute Carrier Family 4, Member 8/10 (SLC4A8/10))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC4A8/10 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- SLC4A8/10 Antibody detects endogenous levels of total SLC4A8/10
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotype
- IgG
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- Application Notes
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- SLC4A8/10 (Solute Carrier Family 4, Member 8/10 (SLC4A8/10))
- Alternative Name
- SLC4A8/10 (SLC4A8/10 Products)
- Background
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Description: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3- exchange with a Na+:HCO3- stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3- from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3- into the cells. Also mediates lithium-dependent HCO3- cotransport. May be regulated by osmolarity.
Gene: SLC4A8
- Molecular Weight
- 140 kDa
- Gene ID
- 9498
- UniProt
- Q2Y0W8, Q6U841
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