CDCA2 antibody (Internal Region)

Catalog No. ABIN6258502

Product Details anti-CDCA2 Antibody

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: CDCA2 Antibody detects endogenous levels of total CDCA2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDCA2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDCA2

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Alternative Name: CDCA2 (CDCA2 Products)

Synonyms: fc32e05 antibody, wu:fc32e05 antibody, wu:fi04h07 antibody, Repo-Man antibody, 2610311M19Rik antibody, AI586158 antibody, cell division cycle associated 2 antibody, si:ch211-244o22.2 antibody, CDCA2 antibody, si:ch211-244o22.2 antibody, Cdca2 antibody

Background:

Description: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Gene: CDCA2

Molecular Weight: 113 kDa

Gene ID: 157313

UniProt: Q69YH5