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TCF7 antibody

TCF7 Reactivity: Human, Mouse WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258455
  • Target See all TCF7 Antibodies
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Reactivity
    • 54
    • 38
    • 17
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 52
    • 4
    • 1
    Rabbit
    Clonality
    • 51
    • 6
    Polyclonal
    Conjugate
    • 36
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This TCF7 antibody is un-conjugated
    Application
    • 41
    • 16
    • 16
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    TCF7 Antibody detects endogenous levels of total TCF7
    Cross-Reactivity
    Human, Mouse (Murine)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotype
    IgG
    Top Product
    Discover our top product TCF7 Primary Antibody
  • Application Notes
    WB 1:500~1:1000, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Alternative Name
    TCF7 (TCF7 Products)
    Synonyms
    TCF-1 antibody, AI465550 antibody, Tcf1 antibody, Xtcf-1 antibody, Xtcf1 antibody, tcf-1 antibody, tcf1 antibody, tcf7 antibody, transcription factor 7 antibody, transcription factor 7, T cell specific antibody, transcription factor 7 S homeolog antibody, TCF7 antibody, Tcf7 antibody, tcf7 antibody, tcf7.S antibody
    Background

    Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.

    Gene: TCF7

    Molecular Weight
    42 kDa
    Gene ID
    6932
    UniProt
    P36402
    Pathways
    WNT Signaling
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