MRPL41 antibody (C-Term)

Catalog No. ABIN6258452

Product Details anti-MRPL41 Antibody

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL41 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MRPL41 Antibody detects endogenous levels of total MRPL41.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MRPL41, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Alternative Name: MRPL41 (MRPL41 Products)

Synonyms: BcDNA:RE19416 antibody, CG12954 antibody, Dmel\\CG12954 antibody, YmL27 antibody, MRP-L27 antibody, Rpml27 antibody, zgc:112362 antibody, BMRP antibody, MRPL27 antibody, RPML27 antibody, L41mt-A antibody, MRP-L41-A antibody, bmrp antibody, mrp-l27 antibody, mrpl27 antibody, mrpl41 antibody, mrpl41-a antibody, mrpl41-b antibody, pig3 antibody, rpml27 antibody, mitochondrial ribosomal protein L41 antibody, 39S ribosomal protein L41, mitochondrial antibody, mitochondrial ribosomal protein L41 L homeolog antibody, mRpL41 antibody, Mrpl41 antibody, MRPL41 antibody, mrpl41 antibody, LOC724790 antibody, mrpl-41 antibody, mrpl41.L antibody

Background:

Description: Component of the mitochondrial ribosome large subunit (PubMed:25278503, PubMed:25838379). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796).

Gene: MRPL41

Molecular Weight: 21 kDa

Gene ID: 64975

UniProt: Q8IXM3

Pathways: p53 Signaling