CDC42EP5 antibody (N-Term)

Catalog No. ABIN6258385

Product Details anti-CDC42EP5 Antibody

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: BORG3 Antibody detects endogenous levels of total BORG3.

Predicted Reactivity: Pig,Bovine,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BORG3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDC42EP5

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Alternative Name: CDC42EP5 (CDC42EP5 Products)

Synonyms: Borg3 antibody, CEP5 antibody, 1700027J19Rik antibody, 2010007O02Rik antibody, C85526 antibody, CDC42 effector protein 5 antibody, CDC42 effector protein (Rho GTPase binding) 5 antibody, CDC42EP5 antibody, Cdc42ep5 antibody

Background:

Description: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity).

Gene: CDC42EP5

Molecular Weight: 22 kDa

Gene ID: 148170

UniProt: Q6NZY7

Pathways: Regulation of Actin Filament Polymerization