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ABHD2 antibody (Internal Region)

ABHD2 Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258379
  • Target See all ABHD2 Antibodies
    ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))
    Binding Specificity
    • 8
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 38
    • 18
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 38
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 16
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABHD2 antibody is un-conjugated
    Application
    • 27
    • 27
    • 20
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ABHD2 Antibody detects endogenous levels of total ABHD2.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ABHD2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ABHD2 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))
    Alternative Name
    ABHD2 (ABHD2 Products)
    Synonyms
    HS1-2 antibody, LABH2 antibody, PHPS1-2 antibody, abhd2 antibody, zgc:55722 antibody, 2210009N18Rik antibody, Labh-2 antibody, zgc:153750 antibody, abhydrolase domain containing 2 antibody, abhydrolase domain containing 2a antibody, abhydrolase domain containing 2b antibody, ABHD2 antibody, Abhd2 antibody, abhd2a antibody, abhd2 antibody, abhd2b antibody
    Background

    Description: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane (PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA) (PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (PubMed:26989199). May also play a role in smooth muscle cells migration (By similarity).

    Gene: ABHD2

    Molecular Weight
    48 kDa
    Gene ID
    11057
    UniProt
    P08910
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