ABHD2 antibody (Internal Region)
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- Target See all ABHD2 Antibodies
- ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABHD2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- ABHD2 Antibody detects endogenous levels of total ABHD2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ABHD2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ABHD2 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))
- Alternative Name
- ABHD2 (ABHD2 Products)
- Synonyms
- HS1-2 antibody, LABH2 antibody, PHPS1-2 antibody, abhd2 antibody, zgc:55722 antibody, 2210009N18Rik antibody, Labh-2 antibody, zgc:153750 antibody, abhydrolase domain containing 2 antibody, abhydrolase domain containing 2a antibody, abhydrolase domain containing 2b antibody, ABHD2 antibody, Abhd2 antibody, abhd2a antibody, abhd2 antibody, abhd2b antibody
- Background
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Description: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane (PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA) (PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (PubMed:26989199). May also play a role in smooth muscle cells migration (By similarity).
Gene: ABHD2
- Molecular Weight
- 48 kDa
- Gene ID
- 11057
- UniProt
- P08910
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