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POU3F2 antibody (N-Term)

POU3F2 Reactivity: Human, Rat, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258305
  • Target See all POU3F2 Antibodies
    POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
    Binding Specificity
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 31
    • 11
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 26
    • 4
    • 1
    Rabbit
    Clonality
    • 28
    • 3
    Polyclonal
    Conjugate
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    This POU3F2 antibody is un-conjugated
    Application
    • 26
    • 18
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    POU3F2 Antibody detects endogenous levels of total POU3F2.
    Predicted Reactivity
    Pig,Bovine
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human POU3F2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POU3F2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
    Alternative Name
    POU3F2 (POU3F2 Products)
    Background

    Description: Transcription factor that plays a key role in neuronal differentiation (By similarity). Binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a non-conserved spacer region of 0, 2, or 3 nucleotides (By similarity). The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Acts downstream of ASCL1, accessing chromatin that has been opened by ASCL1, and promotes transcription of neuronal genes (By similarity).

    Gene: POU3F2

    Molecular Weight
    47 kDa
    Gene ID
    5454
    UniProt
    P20265
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