MLZE antibody (Internal Region)
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- Target See all MLZE Antibodies
- MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MLZE antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- GSDMC Antibody detects endogenous levels of total GSDMC.
- Predicted Reactivity
- Bovine,Sheep
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GSDMC, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MLZE Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))
- Alternative Name
- GSDMC (MLZE Products)
- Synonyms
- Gsdmc1 antibody, Mlze antibody, MLZE antibody, gasdermin C antibody, Gsdmc antibody, GSDMC antibody
- Background
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Description: The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).
Gene: GSDMC
- Molecular Weight
- 58 kDa
- Gene ID
- 56169
- UniProt
- Q9BYG8
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