GRIN2D antibody (Internal Region)
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- Target See all GRIN2D Antibodies
- GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GRIN2D antibody is un-conjugated
- Application
- ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- GRIN2D Antibody detects endogenous levels of total GRIN2D.
- Predicted Reactivity
- Pig,Bovine,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GRIN2D, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GRIN2D Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))
- Alternative Name
- GRIN2D (GRIN2D Products)
- Synonyms
- nr2d antibody, EB11 antibody, GluN2D antibody, NMDAR2D antibody, NR2D antibody, glutamate ionotropic receptor NMDA type subunit 2D antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2D antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog antibody, glutamate receptor, ionotropic, NMDA2D (epsilon 4) antibody, GRIN2D antibody, grin2d.L antibody, grin2d antibody, Grin2d antibody
- Background
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Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750).
Gene: GRIN2D
- Molecular Weight
- 170 kDa
- Gene ID
- 2906
- UniProt
- O15399
- Pathways
- Synaptic Membrane
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