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GPR56 antibody

GPR56 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258204
  • Target See all GPR56 Antibodies
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    Reactivity
    • 39
    • 22
    • 5
    • 4
    • 2
    Human
    Host
    • 35
    • 4
    Rabbit
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR56 antibody is un-conjugated
    Application
    • 32
    • 18
    • 13
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    GPR56 antibody detects endogenous levels of total GPR56
    Cross-Reactivity
    Human
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotype
    IgG
    Top Product
    Discover our top product GPR56 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    Alternative Name
    GPR56 (GPR56 Products)
    Synonyms
    fc49b10 antibody, wu:fc49b10 antibody, BFPP antibody, TM7LN4 antibody, TM7XN1 antibody, Cyt28 antibody, GPR56 antibody, adhesion G protein-coupled receptor G1 antibody, G protein-coupled receptor 56 antibody, ADGRG1 antibody, adgrg1 antibody, Adgrg1 antibody, GPR56 antibody
    Background

    Description: Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity).

    Gene: ADGRG1

    Molecular Weight
    78 kDa
    Gene ID
    9289
    UniProt
    Q9Y653
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