APLP2 antibody (C-Term)

Catalog No. ABIN6257937

Product Details anti-APLP2 Antibody

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: APLP2 Antibody detects endogenous levels of total APLP2.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APLP2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2 (APLP2 Products)

Synonyms: HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, APLP-2 antibody, APPH antibody, APPL2 antibody, CDEBP antibody, AI790698 antibody, Apph antibody, WALPLP2 antibody, aplp2 B antibody, APLP2 antibody, si:dkey-11k4.3 antibody, aplp2 A antibody, MGC86389 antibody, suppression of tumorigenicity 14 antibody, amyloid beta precursor like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 S homeolog antibody, amyloid beta (A4) precursor-like protein 2 L homeolog antibody, ST14 antibody, APLP2 antibody, Aplp2 antibody, aplp2.S antibody, aplp2 antibody, aplp2.L antibody

Background:

Description: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).

Gene: APLP2

Molecular Weight: 87 kDa

Gene ID: 334

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour