ESRP2 antibody (N-Term)

Catalog No. ABIN6257869

Product Details anti-ESRP2 Antibody

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: RBM35B Antibody detects endogenous levels of total RBM35B.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RBM35B, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Alternative Name: ESRP2 (ESRP2 Products)

Synonyms: RBM35B antibody, 9530027K23Rik antibody, Rbm35b antibody, RGD1310855 antibody, cb404 antibody, fa07a06 antibody, rbm35b antibody, sb:cb404 antibody, zgc:77254 antibody, epithelial splicing regulatory protein 2 antibody, microRNA 6773 antibody, ESRP2 antibody, Esrp2 antibody, MIR6773 antibody, esrp2 antibody

Background:

Description: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Gene: ESRP2

Molecular Weight: 78 kDa

Gene ID: 80004

UniProt: Q9H6T0