SFRS7 antibody (Internal Region)

Catalog No. ABIN6257838

Product Details anti-SFRS7 Antibody

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SFRS7 Antibody detects endogenous levels of total SFRS7.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SFRS7, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SFRS7

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Alternative Name: SRSF7 (SFRS7 Products)

Synonyms: 9G8 antibody, AAG3 antibody, SFRS7 antibody, 35kDa antibody, 9430065L19Rik antibody, NX-96 antibody, Sfrs7 antibody, 9g8 antibody, aag3 antibody, sfrs7 antibody, srsf7 antibody, zgc:114203 antibody, serine and arginine rich splicing factor 7 antibody, serine/arginine-rich splicing factor 7 antibody, serine/arginine-rich splicing factor 7 L homeolog antibody, serine/arginine-rich splicing factor 7b antibody, SRSF7 antibody, Srsf7 antibody, srsf7.L antibody, srsf7b antibody

Background:

Description: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

Gene: SRSF7

Molecular Weight: 35 kDa

Gene ID: 6432

UniProt: Q16629