MCM9 antibody (C-Term)

Catalog No. ABIN6257825

Product Details anti-MCM9 Antibody

Target: MCM9 (Minichromosome Maintenance Deficient 9 (MCM9))

Binding Specificity: C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM9 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: MCM9 Antibody detects endogenous levels of total MCM9.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MCM9, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MCM9

Target: MCM9 (Minichromosome Maintenance Deficient 9 (MCM9))

Alternative Name: MCM9 (MCM9 Products)

Synonyms: C6orf61 antibody, MCMDC1 antibody, dJ329L24.1 antibody, dJ329L24.3 antibody, 9030408O17Rik antibody, Gm235 antibody, Mcmdc1 antibody, RGD1560557 antibody, mcm9 antibody, minichromosome maintenance 9 homologous recombination repair factor antibody, minichromosome maintenance 9 homologous recombination repair factor L homeolog antibody, MCM9 antibody, Mcm9 antibody, mcm9.L antibody

Background:

Description: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.

Gene: MCM9

Molecular Weight: ?Isofom 1, 127 , Isoform 2, 44 kDa

Gene ID: 254394

UniProt: Q9NXL9