PSMD11 antibody (Internal Region)
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- Target See all PSMD11 Antibodies
- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMD11 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- PSMD11 Antibody detects endogenous levels of total PSMD11.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PSMD11, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PSMD11 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
- Alternative Name
- PSMD11 (PSMD11 Products)
- Synonyms
- psmd11 antibody, wu:fb55b06 antibody, zgc:56580 antibody, zgc:77763 antibody, Rpn6 antibody, S9 antibody, p44.5 antibody, 1700089D09Rik antibody, 1810019E17Rik antibody, 2610024G20Rik antibody, 2810055C24Rik antibody, C78232 antibody, P44.5 antibody, proteasome 26S subunit, non-ATPase 11 antibody, proteasome 26S subunit, non-ATPase 11b antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antibody, PSMD11 antibody, psmd11b antibody, Psmd11 antibody
- Background
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Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Gene: PSMD11
- Molecular Weight
- 42 kDa
- Gene ID
- 5717
- UniProt
- O00231
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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