BACH2 antibody (Internal Region)

Catalog No. ABIN6257741

Product Details anti-BACH2 Antibody

Target: BACH2 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: BACH2 Antibody detects endogenous levels of total BACH2.

Predicted Reactivity: Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BACH2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for BACH2

Target: BACH2 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2))

Alternative Name: BACH2 (BACH2 Products)

Synonyms: E030004N02Rik antibody, Bach2 antibody, BTBD25 antibody, bach2 antibody, si:dkeyp-4f12.1 antibody, si:dkeyp-4f12.2 antibody, BTB and CNC homology, basic leucine zipper transcription factor 2 antibody, BTB domain and CNC homolog 2 antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 2b antibody, Bach2 antibody, BACH2 antibody, bach2b antibody, bach2 antibody

Background:

Description: Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity).

Gene: BACH2

Molecular Weight: 93 kDa

Gene ID: 60468

UniProt: Q9BYV9