SYCP2 antibody (Internal Region)

Catalog No. ABIN6257733

Product Details anti-SYCP2 Antibody

Target: SYCP2 (Synaptonemal Complex Protein 2 (SYCP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYCP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: SYCP2 Antibody detects endogenous levels of total SYCP2.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SYCP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SYCP2

Target: SYCP2 (Synaptonemal Complex Protein 2 (SYCP2))

Alternative Name: SYCP2 (SYCP2 Products)

Synonyms: SCP2 antibody, 3830402K23Rik antibody, 4930518F03Rik antibody, synaptonemal complex protein 2 antibody, SYCP2 antibody, Sycp2 antibody

Background:

Description: Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.

Gene: SYCP2

Molecular Weight: 45 kDa

Gene ID: 10388

UniProt: Q9BX26

Pathways: M Phase