LMTK3 antibody
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- Target See all LMTK3 Antibodies
- LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LMTK3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- LMTK3 Antibody detects endogenous levels of total LMTK3
- Cross-Reactivity
- Human, Mouse (Murine)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotype
- IgG
- Top Product
- Discover our top product LMTK3 Primary Antibody
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- Application Notes
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))
- Alternative Name
- LMTK3 (LMTK3 Products)
- Synonyms
- LMTK3 antibody, LMR3 antibody, TYKLM3 antibody, BC059845 antibody, aatyk3 antibody, lemur tyrosine kinase 3 antibody, lmtk3 antibody, LMTK3 antibody, Lmtk3 antibody
- Background
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Description: Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).
Gene: LMTK3
- Molecular Weight
- 40 kDa
- UniProt
- Q96Q04
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