RIOK2 antibody (Internal Region)
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- Target See all RIOK2 Antibodies
- RIOK2 (RIO Kinase 2 (RIOK2))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RIOK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Specificity
- RIOK2 Antibody detects endogenous levels of total RIOK2.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RIOK2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product RIOK2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- RIOK2 (RIO Kinase 2 (RIOK2))
- Alternative Name
- RIOK2 (RIOK2 Products)
- Synonyms
- wu:fe48f07 antibody, zgc:55376 antibody, zgc:77493 antibody, rio2 antibody, riok2b antibody, RIO2 antibody, 2010110K24Rik antibody, 2410085M17Rik antibody, RIO kinase 2 antibody, RIO kinase 2 (yeast) antibody, RIO kinase 2 S homeolog antibody, Riok2 antibody, riok2 antibody, RIOK2 antibody, riok2.S antibody
- Background
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Description: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).
Gene: RIOK2
- Molecular Weight
- 63 kDa
- Gene ID
- 55781
- UniProt
- Q9BVS4
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