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PLCE1 antibody

PLCE1 Reactivity: Human, Mouse IHC, WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257434
  • Target See all PLCE1 Antibodies
    PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
    Reactivity
    • 8
    • 2
    • 1
    Human, Mouse
    Host
    • 11
    Rabbit
    Clonality
    • 11
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLCE1 antibody is un-conjugated
    Application
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    Specificity
    PLCE1 antibody detects endogenous levels of total PLCE1
    Cross-Reactivity
    Human, Mouse (Murine)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotype
    IgG
    Top Product
    Discover our top product PLCE1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
    Alternative Name
    PLCE1 (PLCE1 Products)
    Synonyms
    PLCE1 antibody, NPHS3 antibody, PLCE antibody, PPLC antibody, 4933403A21Rik antibody, PLCepsilon antibody, Plce antibody, mKIAA1516 antibody, phospholipase C, epsilon 1 antibody, phospholipase C epsilon 1 antibody, PLCE1 antibody, plce1 antibody, Plce1 antibody
    Background

    Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.

    Gene: PLCE1

    Gene ID
    51196
    UniProt
    Q9P212
    Pathways
    EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
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