PLCE1 antibody
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- Target See all PLCE1 Antibodies
- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLCE1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- Specificity
- PLCE1 antibody detects endogenous levels of total PLCE1
- Cross-Reactivity
- Human, Mouse (Murine)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotype
- IgG
- Top Product
- Discover our top product PLCE1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
- Alternative Name
- PLCE1 (PLCE1 Products)
- Synonyms
- PLCE1 antibody, NPHS3 antibody, PLCE antibody, PPLC antibody, 4933403A21Rik antibody, PLCepsilon antibody, Plce antibody, mKIAA1516 antibody, phospholipase C, epsilon 1 antibody, phospholipase C epsilon 1 antibody, PLCE1 antibody, plce1 antibody, Plce1 antibody
- Background
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Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.
Gene: PLCE1
- Gene ID
- 51196
- UniProt
- Q9P212
- Pathways
- EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
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