NFIL3 antibody (C-Term)

Catalog No. ABIN6257370

Product Details anti-NFIL3 Antibody

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFIL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NFIL3 Antibody detects endogenous levels of total NFIL3.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NFIL3, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NFIL3

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Alternative Name: NFIL3 (NFIL3 Products)

Synonyms: e4bp4 antibody, il3bp1 antibody, nfil3a antibody, nf-il3a antibody, MGC107826 antibody, NFIL3 antibody, E4BP4 antibody, IL3BP1 antibody, NF-IL3A antibody, NFIL3A antibody, E4BP4-1 antibody, zgc:100867 antibody, AV225605 antibody, nuclear factor, interleukin 3 regulated antibody, nuclear factor, interleukin 3 regulated L homeolog antibody, nuclear factor, interleukin 3, regulated antibody, nfil3 antibody, NFIL3 antibody, Nfil3 antibody, nfil3.L antibody

Background:

Description: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death (By similarity).

Gene: NFIL3

Molecular Weight: 51 kDa

Gene ID: 4783

UniProt: Q16649