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MDFI antibody (Internal Region)

MDFI Reactivity: Human, Rat, Mouse ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257357
  • Target See all MDFI Antibodies
    MDFI (MyoD Family Inhibitor (MDFI))
    Binding Specificity
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 33
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 30
    • 2
    • 2
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDFI antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    MDFI Antibody detects endogenous levels of total MDFI.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MDFI, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MDFI Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    MDFI (MyoD Family Inhibitor (MDFI))
    Alternative Name
    MDFI (MDFI Products)
    Synonyms
    MDFI antibody, I-MF antibody, I-mfa antibody, I-mf antibody, RGD1560271 antibody, MyoD family inhibitor antibody, MDFI antibody, Mdfi antibody
    Background

    Description: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

    Gene: MDFI

    Molecular Weight
    25 kDa
    Gene ID
    4188
    UniProt
    Q99750
    Pathways
    Maintenance of Protein Location
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