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MYO9B antibody (N-Term)

MYO9B Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257337
  • Target See all MYO9B Antibodies
    MYO9B (Myosin IXB (MYO9B))
    Binding Specificity
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 11
    • 1
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYO9B antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    MYO9B Antibody detects endogenous levels of total MYO9B.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MYO9B, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    MYO9B (Myosin IXB (MYO9B))
    Alternative Name
    MYO9B (MYO9B Products)
    Synonyms
    CELIAC4 antibody, MYR5 antibody, MYO9B antibody, fb53f01 antibody, wu:fb53f01 antibody, wu:fc47c07 antibody, si:dkeyp-66d1.8 antibody, myosin IXB antibody, myosin IXb antibody, unconventional myosin-IXb antibody, MYO9B antibody, Myo9b antibody, myo9b antibody, LOC100450445 antibody
    Background

    Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).

    Gene: MYO9B

    Molecular Weight
    250 kDa
    Gene ID
    4650
    UniProt
    Q13459
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