Meningioma 1 antibody (Internal Region)

Catalog No. ABIN6257329

Product Details anti-Meningioma 1 Antibody

Target: Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Meningioma 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: MN1 Antibody detects endogenous levels of total MN1.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MN1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Meningioma 1

Target: Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))

Alternative Name: MN1 (MN1 Products)

Synonyms: MGCR antibody, MGCR1 antibody, MGCR1-PEN antibody, dJ353E16.2 antibody, MN1 proto-oncogene, transcriptional regulator antibody, MN1 antibody

Background:

Description: Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity). May play a role in tumor suppression (Probable).

Gene: MN1

Molecular Weight: 135 kDa

Gene ID: 4330

UniProt: Q10571