MLF1IP antibody (N-Term)

Catalog No. ABIN6257324

Product Details anti-MLF1IP Antibody

Target: MLF1IP (MLF1 Interacting Protein (MLF1IP))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLF1IP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: CENPU Antibody detects endogenous levels of total CENPU.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CENPU, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MLF1IP

Target: MLF1IP (MLF1 Interacting Protein (MLF1IP))

Alternative Name: CENPU (MLF1IP Products)

Synonyms: MGC147270 antibody, CENP50 antibody, CENPU antibody, CENPU50 antibody, KLIP1 antibody, PBIP1 antibody, CENP-U antibody, CENP-50 antibody, 1700029A22Rik antibody, centromere protein U antibody, MLF1 interacting protein antibody, cenpu antibody, MLF1IP antibody, CENPU antibody, Cenpu antibody

Background:

Description: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.

Gene: CENPU

Molecular Weight: 48 kDa

Gene ID: 79682

UniProt: Q71F23