HLA-DOB antibody

Catalog No. ABIN6257256

Product Details anti-HLA-DOB Antibody

Target: HLA-DOB (Major Histocompatibility Complex, Class II, DO beta (HLA-DOB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DOB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: HLA-DOB Antibody detects endogenous levels of total HLA-DOB

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500~1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for HLA-DOB

Target: HLA-DOB (Major Histocompatibility Complex, Class II, DO beta (HLA-DOB))

Alternative Name: HLA-DOB (HLA-DOB Products)

Synonyms: DOB antibody, major histocompatibility complex, class II, DO beta antibody, HLA-DOB antibody, PATR-DOB antibody

Background:

Description: Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.

Gene: HLA-DOB

Molecular Weight: 31 kDa

Gene ID: 3112

UniProt: P13765

Pathways: Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response