GRIP1 antibody (Internal Region)

Catalog No. ABIN6257242

Product Details anti-GRIP1 Antibody

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: GRIP1 Antibody detects endogenous levels of total GRIP1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GRIP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for GRIP1

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Alternative Name: GRIP1 (GRIP1 Products)

Synonyms: GRIP antibody, 4931400F03Rik antibody, eb antibody, grip antibody, xgrip1 antibody, GRIP1 antibody, si:dkey-244b23.1 antibody, si:dkey-6a5.1 antibody, glutamate receptor interacting protein 1 antibody, glutamate receptor interacting protein 1 S homeolog antibody, glutamate receptor-interacting protein 1 antibody, GRIP1 antibody, Grip1 antibody, grip1.S antibody, LOC525592 antibody, grip1 antibody

Background:

Description: May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (PubMed:10197531). Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).

Gene: GRIP1

Molecular Weight: 117 kDa

Gene ID: 23426

UniProt: Q9Y3R0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway