G Protein-Coupled Receptor 132 antibody (C-Term)

Catalog No. ABIN6257199

Product Details anti-G Protein-Coupled Receptor 132 Antibody

Target: G Protein-Coupled Receptor 132 (GPR132)

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G Protein-Coupled Receptor 132 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: GPR132 Antibody detects endogenous levels of total GPR132.

Predicted Reactivity: Pig,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPR132, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for G Protein-Coupled Receptor 132

Target: G Protein-Coupled Receptor 132 (GPR132)

Alternative Name: GPR132 (GPR132 Products)

Synonyms: G2A antibody, G2a antibody, G protein-coupled receptor 132 antibody, GPR132 antibody, gpr132 antibody, Gpr132 antibody

Background:

Description: May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic  pH through proton-sensing activity.

Gene: GPR132

Molecular Weight: 42 kDa

Gene ID: 29933

UniProt: Q9UNW8