FPR2 antibody (C-Term)

Catalog No. ABIN6257187

Product Details anti-FPR2 Antibody

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificity: FPRL1 Antibody detects endogenous levels of total FPRL1.

Predicted Reactivity: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FPRL1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPR2 (FPR2 Products)

Synonyms: ALXR antibody, FMLP-R-II antibody, FMLPX antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, LXA4R antibody, E330010I07Rik antibody, Fpr-rs2 antibody, Fprl1 antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-I antibody, FPR2 antibody, formyl peptide receptor 2 antibody, formyl peptide receptor 3 antibody, N-formyl peptide receptor 2 antibody, FPR2 antibody, Fpr2 antibody, Fpr3 antibody, LOC100444626 antibody

Background:

Description: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Gene: FPR2

Molecular Weight: 38 kDa

Gene ID: 2358

UniProt: P25090