Foxk1 antibody (Internal Region)
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- Target See all Foxk1 Antibodies
- Foxk1 (Forkhead Box K1 (Foxk1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Foxk1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- FOXK1 Antibody detects endogenous levels of total FOXK1.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human FOXK1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product Foxk1 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Foxk1 (Forkhead Box K1 (Foxk1))
- Alternative Name
- FOXK1 (Foxk1 Products)
- Synonyms
- FOXK1L antibody, A630048H08Rik antibody, AI463295 antibody, ENSMUSG00000075577 antibody, Gm10868 antibody, Mnf antibody, RGD1309643 antibody, wu:fi75f05 antibody, zgc:66237 antibody, FOXK1 antibody, forkhead box K1 antibody, FOXK1 antibody, Foxk1 antibody, foxk1 antibody
- Background
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Description: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene (By similarity). Important regulatory factor of the myogenic progenitor cell population (By similarity). Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells (By similarity). Represses myogenic differentiation by inhibiting MEFC acitivity (By similarity). Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli (By similarity). Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair (By similarity). Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus (PubMed:25805136). Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression (PubMed:25852164).
Gene: FOXK1
- Molecular Weight
- 78 kDa
- Gene ID
- 221937
- UniProt
- P85037
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