INTS6 antibody (C-Term)
-
- Target See all INTS6 Antibodies
- INTS6 (Integrator Complex Subunit 6 (INTS6))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This INTS6 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Specificity
- INT6 Antibody detects endogenous levels of total INT6.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human INT6, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product INTS6 Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
-
- Target
- INTS6 (Integrator Complex Subunit 6 (INTS6))
- Alternative Name
- INTS6 (INTS6 Products)
- Background
-
Description: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).
Gene: INTS6
- Molecular Weight
- 117 kDa
- Gene ID
- 26512
- UniProt
- Q9UL03
-