DNAJB11 antibody (N-Term)

Catalog No. ABIN6257145

Product Details anti-DNAJB11 Antibody

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJB11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: DNAJB11 Antibody detects endogenous levels of total DNAJB11.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DNAJB11, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DNAJB11

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Alternative Name: DNAJB11 (DNAJB11 Products)

Synonyms: MGC75796 antibody, MGC81924 antibody, ABBP-2 antibody, ABBP2 antibody, DJ9 antibody, Dj-9 antibody, EDJ antibody, ERdj3 antibody, ERj3 antibody, ERj3p antibody, PRO1080 antibody, UNQ537 antibody, hDj-9 antibody, 1810031F23Rik antibody, AL024055 antibody, Dj9 antibody, LRRGT00084 antibody, cb954 antibody, DnaJ heat shock protein family (Hsp40) member B11 antibody, DnaJ heat shock protein family (Hsp40) member B11 S homeolog antibody, DnaJ (Hsp40) homolog, subfamily B, member 11 antibody, dnajb11 antibody, DNAJB11 antibody, dnajb11.S antibody, Dnajb11 antibody

Background:

Description: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Gene: DNAJB11

Molecular Weight: 40 kDa

Gene ID: 51726

UniProt: Q9UBS4

Pathways: ER-Nucleus Signaling