OPRD1 antibody (C-Term)
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- Target See all OPRD1 Antibodies
- OPRD1 (Opioid Receptor, delta 1 (OPRD1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OPRD1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- OPRD1 Antibody detects endogenous levels of total OPRD1.
- Predicted Reactivity
- Bovine,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human OPRD1, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product OPRD1 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- OPRD1 (Opioid Receptor, delta 1 (OPRD1))
- Alternative Name
- OPRD1 (OPRD1 Products)
- Synonyms
- OPRD antibody, DOR-1 antibody, Nbor antibody, mDOR antibody, opioid receptor delta 1 antibody, opioid receptor, delta 1 antibody, OPRD1 antibody, Oprd1 antibody
- Background
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Description: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Gene: OPRD1
- Molecular Weight
- 36 kDa
- Gene ID
- 4985
- UniProt
- P41143
- Pathways
- Protein targeting to Nucleus
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