GARP antibody (Internal Region)

Catalog No. ABIN6257117

Product Details anti-GARP Antibody

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GARP antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CNGB1 Antibody detects endogenous levels of total CNGB1.

Predicted Reactivity: Pig,Bovine,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNGB1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GARP

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Alternative Name: CNGB1 (CNGB1 Products)

Synonyms: CNCG2 antibody, CNCG3L antibody, CNCG4 antibody, CNG4 antibody, CNGB1B antibody, GAR1 antibody, GARP antibody, RCNC2 antibody, RCNCb antibody, RCNCbeta antibody, RP45 antibody, Gm1959 antibody, Cngb1b antibody, CNGB1 antibody, si:ch211-160j6.1 antibody, cyclic nucleotide gated channel beta 1 antibody, cyclic nucleotide gated channel beta 1a antibody, CNGB1 antibody, Cngb1 antibody, cngb1a antibody

Background:

Description: Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.

Gene: CNGB1

Molecular Weight: 102 kDa

Gene ID: 1258

UniProt: Q14028

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction