CSNK1A1 antibody (Internal Region)

Catalog No. ABIN6257059

Product Details anti-CSNK1A1 Antibody

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Casein Kinase 1 alpha Antibody detects endogenous levels of total Casein Kinase 1 alpha.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Casein Kinase 1 alpha, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: CSNK1A1 (CSNK1A1 Products)

Synonyms: CK1 antibody, CK1a antibody, CKIa antibody, HLCDGP1 antibody, PRO2975 antibody, 2610208K14Rik antibody, 4632404G05Rik antibody, 5430427P18Rik antibody, Csnk1a antibody, CHUNP6894 antibody, ck1alpha antibody, wu:fb65a02 antibody, wu:fi30h04 antibody, wu:fj19c11 antibody, zgc:92158 antibody, KER1 antibody, ck1 antibody, CKIALPHA antibody, CK-II antibody, CSNK2A1 antibody, CG2028 antibody, CK I antibody, CK1alpha antibody, CKI antibody, CKI alpha antibody, CKIalpha antibody, CkIa antibody, Dmel\\CG2028 antibody, PKA-C antibody, anon-WO03040301.93 antibody, anon-WO03040301.95 antibody, ck1a antibody, dmCK1 antibody, dmckI antibody, l(1)G0492 antibody, casein kinase 1 alpha 1 antibody, casein kinase 1, alpha 1 antibody, keratin 1 antibody, casein kinase 1 alpha 1 L homeolog antibody, casein kinase 2 alpha 1 antibody, Casein kinase Ialpha antibody, CSNK1A1 antibody, Csnk1a1 antibody, csnk1a1 antibody, KRT1 antibody, csnk1a1.L antibody, CSNK2A1 antibody, CkIalpha antibody

Background:

Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).

Gene: CSNK1A1

Molecular Weight: 35 kDa

Gene ID: 1452

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling