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IQGAP1 antibody (N-Term)

IQGAP1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256871
  • Target See all IQGAP1 Antibodies
    IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
    Binding Specificity
    • 15
    • 8
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 62
    • 25
    • 20
    • 15
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 56
    • 6
    • 1
    Rabbit
    Clonality
    • 49
    • 14
    Polyclonal
    Conjugate
    • 25
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IQGAP1 antibody is un-conjugated
    Application
    • 47
    • 24
    • 15
    • 14
    • 8
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    IQGAP1 Antibody detects endogenous levels of total IQGAP1.
    Predicted Reactivity
    Pig,Bovine,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IQGAP1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IQGAP1 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
    Alternative Name
    IQGAP1 (IQGAP1 Products)
    Synonyms
    HUMORFA01 antibody, SAR1 antibody, p195 antibody, AA682088 antibody, D7Ertd237e antibody, D7Ertd257e antibody, mKIAA0051 antibody, IQ motif containing GTPase activating protein 1 antibody, IQGAP1 antibody, Iqgap1 antibody
    Background

    Description: Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).

    Gene: IQGAP1

    Molecular Weight
    190 kDa
    Gene ID
    8826
    UniProt
    P46940
    Pathways
    Signaling Events mediated by VEGFR1 and VEGFR2
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