MRGPRD antibody (C-Term)

Catalog No. ABIN6256842

Product Details anti-MRGPRD Antibody

Target: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGPRD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: MRGRD Antibody detects endogenous levels of total MRGRD.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MRGRD, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MRGPRD

Target: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Alternative Name: MRGPRD (MRGPRD Products)

Synonyms: MRGD antibody, TGR7 antibody, Gm499 antibody, MrgD antibody, Mrgd antibody, MAS related GPR family member D antibody, mas-related G-protein coupled receptor member D antibody, MAS-related GPR, member D antibody, MRGPRD antibody, LOC615853 antibody, Mrgprd antibody

Background:

Description: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca2+ influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

Gene: MRGPRD

Molecular Weight: 41 kDa,10 % SDS-PAGE

Gene ID: 116512

UniProt: Q8TDS7