Tumor Protein p73 antibody (pTyr99)
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- Target See all Tumor Protein p73 (TP73) Antibodies
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Binding Specificity
- pTyr99
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Tumor Protein p73 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Phospho-p73 (Tyr99) Antibody detects endogenous levels of p73 only when phosphorylated at Tyrosine 99.
- Predicted Reactivity
- Pig,Bovine,Sheep,Dog,Chicken
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human p73 around the phosphorylation site of Tyr99.
- Isotype
- IgG
- Top Product
- Discover our top product TP73 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:1000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
- Alternative Name
- TP73 (TP73 Products)
- Synonyms
- P73 antibody, Trp73 antibody, TP73 antibody, tp73 antibody, Tp73 antibody, p73 antibody, TAp73 antibody, zp73theta antibody, tumor protein p73 antibody, transformation related protein 73 antibody, TP73 antibody, Tp73 antibody, tp73 antibody, Trp73 antibody
- Background
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Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Gene: TP73
- Molecular Weight
- 80kDa
- Gene ID
- 7161
- UniProt
- O15350
- Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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