STAT5 A/B antibody (pSer725, pSer730)
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- Target See all STAT5 A/B products
- STAT5 A/B
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Binding Specificity
- pSer725, pSer730
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STAT5 A/B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Phospho-STAT5A/B (Ser725/730) Antibody detects endogenous levels of STAT5A/B only when phosphorylated at Serine 725/730
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human STAT5A/B around the phosphorylation site of Serine 725/730
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- STAT5 A/B
- Alternative Name
- STAT5A/B (STAT5 A/B Products)
- Background
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Description: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Gene: STAT5A
- Molecular Weight
- 90kDa
- Gene ID
- 6776
- UniProt
- P42229, P51692
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