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Aryl Hydrocarbon Receptor antibody (pSer36)

AHR Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256291
  • Target See all Aryl Hydrocarbon Receptor (AHR) Antibodies
    Aryl Hydrocarbon Receptor (AHR)
    Binding Specificity
    • 15
    • 10
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer36
    Reactivity
    • 100
    • 72
    • 39
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 96
    • 10
    • 5
    • 2
    Rabbit
    Clonality
    • 96
    • 17
    Polyclonal
    Conjugate
    • 64
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Aryl Hydrocarbon Receptor antibody is un-conjugated
    Application
    • 74
    • 33
    • 31
    • 24
    • 20
    • 19
    • 14
    • 13
    • 13
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-AhR (Ser36) Antibody detects endogenous levels of AhR only when phosphorylated at Serine 36
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human AhR around the phosphorylation site of Serine 36
    Isotype
    IgG
    Top Product
    Discover our top product AHR Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    Aryl Hydrocarbon Receptor (AHR)
    Alternative Name
    AhR (AHR Products)
    Synonyms
    AHR antibody, ahr1 antibody, ahr antibody, bHLHe76 antibody, Ah antibody, Ahh antibody, Ahre antibody, In antibody, aryl hydrocarbon receptor S homeolog antibody, aryl hydrocarbon receptor antibody, aryl-hydrocarbon receptor antibody, ahr.S antibody, AHR antibody, ahr antibody, Ahr antibody
    Background

    Description: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

    Gene: AHR

    Molecular Weight
    90kDa
    Gene ID
    196
    UniProt
    P35869, A9YTQ3
    Pathways
    Regulation of Cell Size
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