HNF4A antibody (pSer313)

Catalog No. ABIN6256265

Product Details anti-HNF4A Antibody

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Binding Specificity: pSer313

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Phospho-HNF4 alpha (Ser313) Antibody detects endogenous levels of HNF4 alpha only when phosphorylated at Serine 313.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human HNF4 alpha around the phosphorylation site of Ser313.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HNF4A

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Alternative Name: HNF4A (HNF4A Products)

Synonyms: HNF4A antibody, HNF4alpha antibody, CG9310 antibody, DmHNF4 antibody, Dmel\\CG9310 antibody, HNF-4 antibody, HNF-4(D) antibody, HNF4 antibody, Hnf-4 antibody, Hnf-4h antibody, NR2A4 antibody, dHNF-4 antibody, dHNF4 antibody, Hnf4 antibody, Hnf4alpha antibody, MODY1 antibody, Nr2a1 antibody, Tcf14 antibody, HNF4a7 antibody, HNF4a8 antibody, HNF4a9 antibody, MODY antibody, NR2A1 antibody, NR2A21 antibody, TCF antibody, TCF14 antibody, HNF-4alpha antibody, fb58h09 antibody, id:ibd1279 antibody, wu:fb58h09 antibody, hnf4 antibody, nr2a1 antibody, hepatocyte nuclear factor 4 alpha antibody, Hepatocyte nuclear factor 4 antibody, hepatic nuclear factor 4, alpha antibody, hepatocyte nuclear factor 4, alpha antibody, hepatocyte nuclear factor 4 alpha S homeolog antibody, HNF4A antibody, hnf4a antibody, Hnf4 antibody, Hnf4a antibody, hnf4a.S antibody

Background:

Description: Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.

Gene: HNF4A

Molecular Weight: 52kDa

Gene ID: 3172

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process