CDC37 antibody (pSer13)

Catalog No. ABIN6256126

Product Details anti-CDC37 Antibody

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Binding Specificity: pSer13

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC37 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Phospho-CDC37 (Ser13) Antibody detects endogenous levels of CDC37 only when phosphorylated at Serine 13.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human CDC37 around the phosphorylation site of Ser13.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDC37

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Alternative Name: CDC37 (CDC37 Products)

Synonyms: CG12019 antibody, CPDR-1 antibody, CPDR-2 antibody, DROCPDR antibody, Dmel\\CG12019 antibody, E(sev)3B antibody, cdc37 antibody, Afu4g10010 antibody, P50CDC37 antibody, p50 antibody, p50Cdc37 antibody, CG12019 gene product from transcript CG12019-RA antibody, cell division cycle 37 homolog antibody, Hsp90 co-chaperone Cdc37 antibody, Cdc37p antibody, cell division cycle 37 antibody, Cdc37 antibody, cdc37 antibody, AFUA_4G10010 antibody, CDC37 antibody

Background:

Description: Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206).

Gene: CDC37

Molecular Weight: 44kDa

Gene ID: 11140

UniProt: Q16543