BIK antibody (pThr33)

Catalog No. ABIN6255669

Product Details anti-BIK Antibody

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Binding Specificity: pThr33

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Phospho-BIK (Thr33) Antibody detects endogenous levels of BIK only when phosphorylated at Threonine 33.

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human BIK around the phosphorylation site of Thr33.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for BIK

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Alternative Name: BIK (BIK Products)

Synonyms: BIK antibody, Biklk antibody, Blk antibody, Nbk antibody, BIP1 antibody, BP4 antibody, NBK antibody, si:dkey-31f5.6 antibody, BCL2 interacting killer antibody, BCL2-interacting killer antibody, BCL2-interacting killer (apoptosis-inducing) antibody, BIK antibody, Bik antibody, bik antibody

Background:

Description: Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.

Gene: BIK

Molecular Weight: 30kDa

Gene ID: 638

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity