CaMK2 alpha/beta/delta antibody (pThr305)
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- Target See all CaMK2 alpha/beta/delta products
- CaMK2 alpha/beta/delta
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Binding Specificity
- pThr305
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CaMK2 alpha/beta/delta antibody is un-conjugated
- Application
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Phospho-CaMK2 alpha/ beta/ delta (Thr305) Antibody detects endogenous levels of CaMK2 alpha/ beta/ delta only when phosphorylated at Threonine 305
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human CaMK2 alpha/ beta/ delta around the phosphorylation site of Threonine 305
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- CaMK2 alpha/beta/delta
- Alternative Name
- CaMK2 alpha/ beta/ delta (CaMK2 alpha/beta/delta Products)
- Background
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Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Gene: CAMK2A
- Molecular Weight
- 54kDa
- Gene ID
- 815
- UniProt
- Q9UQM7, Q13554, Q13557
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