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CaMK2 alpha/beta/delta antibody (pThr305)

Reactivity: Human, Mouse, Rat IHC, ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6255659
  • Target See all CaMK2 alpha/beta/delta products
    CaMK2 alpha/beta/delta
    Binding Specificity
    • 2
    • 2
    • 1
    pThr305
    Reactivity
    Human, Mouse, Rat
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This CaMK2 alpha/beta/delta antibody is un-conjugated
    Application
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-CaMK2 alpha/ beta/ delta (Thr305) Antibody detects endogenous levels of CaMK2 alpha/ beta/ delta only when phosphorylated at Threonine 305
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human CaMK2 alpha/ beta/ delta around the phosphorylation site of Threonine 305
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    CaMK2 alpha/beta/delta
    Alternative Name
    CaMK2 alpha/ beta/ delta (CaMK2 alpha/beta/delta Products)
    Background

    Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

    Gene: CAMK2A

    Molecular Weight
    54kDa
    Gene ID
    815
    UniProt
    Q9UQM7, Q13554, Q13557
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